Ibogaine will work to restore dopamine, adrenaline, endorphins and serotonin generation in your body, which brings balance and neuroplasticity to your brain. When a person goes through with an ibogaine treatment, the plant medicine binds to several receptor sites in the brain, including the μ-opioid receptor, more commonly known as “Mu,” and the NMDA receptor.
Ibogaine works by simultaneously binding to the Mu and NMDA receptor sites in the brain. It serves as an antagonist (or blocker) of opioid dependence while performing as an agonist (or activator) of new thought processes, memories, and emotional balance. Essentially, the desire for more opioids is blocked while the brain experiences a pleasant psychoactive sensation. After an ibogaine treatment is complete, the mind associates sobriety with contentment and effectively ends the addictive cycle. Read more about the clinical data available and pharmacology of ibogaine in this article.